About Metronidazole 400mg Tablet

Metronidazole is commonly prescribed as an antibiotic for bacterial vaginosis. Its active ingredient, also called Metronidazole, effectively targets and treats bacterial infections. Available in tablets, gel, cream, and liquid forms, it is marketed as both a generic drug and under the brand name Flagyl.

How do Metronidazole tablets work?

Metronidazole works by killing the anaerobic bacteria that cause infection. Lactobacilli bacteria replace the anaerobic bacteria and provide a naturally balanced environment in the vagina.

Metronidazole tablets and pregnancy

Research shows that bacterial vaginosis can complicate your pregnancy. There is no proven evidence that metronidazole can cause preterm delivery, low birth weight, stillbirth, or birth defects.

• While pregnant you should not take a single high dose of metronidazole.
• Pregnant mothers should seek medical advice before taking Metronidazole

Metronidazole tablets should not be taken during the first 3 months of pregnancy and are not recommended for use during the rest of the pregnancy.

Is metronidazole safe during breastfeeding?

If you're breastfeeding, pause while taking Metronidazole tablets and wait 12-24 hours after finishing the course before breastfeeding again.

Ensure you inform your doctor that you are Breastfeeding to receive the right instructions for the medication.

Alternative treatment

Metronidazole 400mg tablets can cause different reactions in different patients. Some patients may prefer taking other forms of medication to treat bacterial vaginosis. Examples of alternative treatments that can be used in place of metronidazole include:

Zidoval vaginal gel (Metronidazole 0.75% vaginal gel):

Zidoval vaginal gel treatment contains metronidazole. This treatment is taken by inserting it into the vagina for 5 consecutive days before going to bed.

Dalacin cream.(Clindamycin 2% vaginal cream)

You can treat bacterial vaginosis by inserting Dalacin cream into the vagina using an applicator. Dalacin cream works effectively when taken as a 7-day course.

Clindamycin tablets

Clindamycin tablets are recommended for pregnant women. It is available as a 300mg tablet and should be taken 2 times a day for 7 days.

Other medications and Metronidazole.

You should inform your doctor if you are under any other treatment before taking Metronidazole. Speak to your doctor before taking Metronidazole if you are taking the following medicines.

• Busulfan. is a type of medicine used to treat leukemia
• Treatments used to treat epilepsy
• Lithium
• Fluorouracil
• Ciclosporin
• Phenobarbital

How can you reduce the risk of getting bacterial vaginosis?

You can reduce the risk of getting bacterial vaginosis by observing the following lifestyle habits.

• Avoid smoking
• Avoid using vaginal deodorants
• Always take a shower instead of a bath
• Avoid using strong detergent when washing your underwear
• Avoid using shower gel, bubble baths, perfumed soap, and antiseptic in the bath
• To wash your genital area use water and plain soap. Avoid using creams to wash your genital area.

Reviewed By

https://www.medicines.org.uk/emc/files/pil.11952.pdf

Dosage

Dosage for Metronidazole tablets

Metronidazole is available in two doses:400mg, taken 2 times a day for 7 consecutive days, and 2g single doses where you take 5 tablets at once.

The 7-day dose is recommended for people who get Bacterial vaginosis often.

Warnings

Who should not take metronidazole 400mg tablets?

You should always consult a doctor if you are under any other medication or suffering from other illnesses. The following are groups of people who should consult a doctor before taking Metronidazole.

• If you are having liver problems
• If you have a dialysis appointment
• If you are unable to stop taking alcohol 
• If you have a history of allergic reactions caused by metronidazole medicine

Warning and precautions

Always follow doctors' advice while taking Metronidazole. Avoid taking alcohol when under Metronidazole treatment. You should also not take alcohol 2 days after completing your dosage.

• Visit a doctor if you are still experiencing bacterial vaginosis symptoms even after taking Metronidazole.

Avoid taking Metronidazole if you are having neurological diseases. Metronidazole accelerates neurological diseases.

Metronidazole can make you dizzy. Alcohol makes you even more dizzy. Avoid driving or using machines after taking this medicine. If you work on tasks that require more alertness, ensure to take enough rest after taking metronidazole before proceeding with your tasks.

Do not take metronidazole if you are having or planning to have immunization or vaccinations. This treatment makes vaccines not work effectively.

Side effects of Metronidazole 400mg tablets 

Like any other medicine, you may experience various side effects or not. Some of the side effects of taking Metronidazole include:

Common side effects.

They are side effects that you can manage by yourself, although when symptoms persist seek medical advice.

• Headaches 
• Sleeping for longer hours than usual
• Convulsions
• Jaundice.Yellowing of the skin and eyes
• Eyesight problems such as blurred vision

Severe side effects.

Stop taking Metronidazole treatments if you experience severe side effects Get a doctor's advice if you experience the following side effects.

• Swollen feet, hand lips, face and ankles 
• Itchiness
• Rashes.Rashes with blisters,
• Peeling of the skin
• Bleeding of the skin
• Stiff neck 
• Difficulty in breathing
• Experiencing higher temperatures than normal 
• Experiencing difficulty while speaking 

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