Cytisine

cytisine quit smoking tablets UK
  • cytisine quit smoking tablets UK

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Cytisine

From£149.99
Fastest delivery:
Monday, 03 Feb 2025
  • Medication features

    Stop Smoking Tablets

    Cytisine 1.5mg Smoking Cessation Tablets are a prescription-only treatment that helps reduce the urge to smoke, increasing your chances of quitting. Approved in the UK, it is effective within 25 days to stop using nicotine-containing products. Each tablet contains 1.5mg of cytisine, with 100 tablets per pack. Suitable for adults aged 18 and over.

    • Doubles your chances of quitting smoking
    • Contains no nicotine
    • Relieves cravings and withdrawal symptoms

     

    Ashcroft
    Order cytisine 1.5mg tablets online from UK registered Pharmacy Number 1039428.

Order Monday to Friday before 14:00pm to guarantee next day delivery

Fastest delivery: Monday, 03 Feb 2025

Overview

NOTE: After selecting this product, you will need to complete a short assessment, so we can make sure this medication is suitable for you.

Buy Cytisine online in UK

How to order cytisine 1.5mg tablets online for UK delivery:

If you want to buy Cytisine online, head over to Ashcroft Pharmacy (UK-registered online pharmacy). We offer free online consultations and medications at competitive prices. Just answer a few questions and our pharmacists will evaluate whether Cytisine is safe for you.

Once approved, we will dispatch your order to your doorstep via our fast, discreet delivery process.

Cytisine for quit smoking

In the early 1950s, two Bulgarian pharmacologists, Dr. Hristo Dobrev, and Professor Dimitar Paskov, developed Cytisine, a compound with a significant pharmacological effect on the brain’s nicotinic acetylcholine receptors (nAChRs).

Cytisine works by binding to these receptors, mimicking the effects of nicotine to help reduce cravings and withdrawal symptoms.

This makes it an effective aid for quitting nicotine-containing products, as it allows users to overcome their addiction to smoking gradually.

Cytisine uses: How does Cytisine help to quit smoking

Cytisine, an alkaloid, is extracted from parts of many plant species, particularly from Laburnum seeds. Its mode of action is similar to Varenicline. It is a partial agonist of the alpha-4 beta-2 nicotinic acetylcholine receptors and acts in such a way that:

  • âś… Limit the activation of neural pathways and control urges to smoke.

  • âś… Block the nicotinic receptors in your brain, and do not let the nicotine from your cigarette attach itself to these receptors.

Cytisine quit smoking tablet is a helpful option for:

  • âś… Smokers who are motivated to quit smoking

  • âś… Those who have tried other stop-smoking methods but found them useless

No doubt, Cytisine's success rate is higher than other stop-smoking options. It also has lower relapse rates than others and is twice as effective as placebo. 

However, if you want to get the most out of Cytisine, combine it with behavioral support such as support groups, counseling, and education materials, helping you quit smoking permanently.

How to take Cytisine tablets?

You must take Cytisine for smoking cessation according to your doctor’s instructions and prescription, such as:

  • âś… Swallow the whole tablet with a glass of water.

  • âś… Do not take more or less than the prescribed dose, as it can result in adverse effects.

  • âś… Start taking Cytisine and select your quit date no later than the 5th day of treatment. After the quit date, do not smoke, as it may result in adverse effects and worsen the harmful effects of nicotine. 

  • âś… It is a 25-day treatment (100 tablets). If you slip or relapse, resume your treatment in 2-3 months. Taking it for 25 days is as effective as NRT (nicotine replacement therapy). 

However, taking Cytisine for up to 12 weeks is more effective or as effective asvarenicline

How long does Cytisine take to work?

Cytisine starts working within a few days of taking it. Although its course of treatment is 25 days, you will start noticing a reduction in cravings and withdrawal symptoms quite soon.

Most people experience a decrease in their urge to smoke within the first week of taking Cytisine. However, you must finish the treatment course as the effectiveness varies from person to person, depending on current health, commitment to treatment, or adherence to medical advice.

Missed dose

If you forget to take a Cytisine dose, take it as soon as you remember. If it is time for your next dose, skip the missed one and take your next dose at the normal time. Do not take double or extra doses to make up for the missed one. 

Overdose 

If you have taken too many Cytisine pills, you may experience unusual side effects such as:

  • âś… Malaise
  • âś… Nausea
  • âś… Vomiting
  • âś… Increased heart rate (tachycardia)
  • âś… Fluctuations in blood pressure
  • âś… Breathing problems
  • âś… Blurred vision
  • âś… Convulsions 

If you get any symptoms after taking too much Cytisine, stop taking this medicine and visit your doctor immediately for gastric lavage (stomach wash).

Efficacy and effectiveness: Is Cytisine safe?

Cytisine is a safe and effective stop-smoking medication, significantly improving quit rates. The large trial in 2011 and several Cytisine smoking cessation studies claimed that it is a safe drug with an approved 25-day dose schedule.

The open-label trial in New Zealand found it more effective than nicotine replacement therapy (NRT) and has higher quit rates.

The studies also showed that the side effects found in varenicline are less common for Cytisine. The most common side effects of Cytisine are sleep disturbance and gastric symptoms. 

What happens if you smoke while taking Cytisine?

If you smoke while taking Cytisine, the effectiveness of the medication will be reduced. Cytisine binds to nicotinic receptors in your brain, alleviating withdrawal symptoms and cravings for cigarettes.

If you continue to smoke while taking Cytisine, it will introduce nicotine into your system and let it compete with Cytisine for the same receptors.

It reduces Cytisine’s impact and increases the risk of adverse effects such as dizziness, nausea, suicidal thoughts, feelings of anxiety or depression, or cardiovascular strain.

To enhance the effectiveness of Cytisine and ensure safety, quit smoking completely or within 5 days when taking Cytisine tablets. 

Cytisine UK: Alternative smoking cessation treatments

If Cytisine does not suit you, the alternative smoking cessation treatments are:

  • NRT (nicotine replacement therapy)

❇️ Champix

Champix is the brand name for Varenicline, a prescription medication used to help people quit smoking. It is one of the most effective treatments for smoking cessation, working by reducing cravings and withdrawal symptoms while also decreasing the rewarding effects of smoking.

❇️ Varenicline

Varenicline is a prescription medication used to help people quit smoking. It is sold under the brand name Champix in many countries and Chantix in the United States.

❇️ Zyban

Zyban tablet is another effective medication for quitting smoking. Also known as bupropion hydrochloride, it’s an antidepressant that works by reducing cravings and withdrawal symptoms associated with nicotine addiction. Zyban affects brain chemicals like dopamine and norepinephrine, making it easier to stop smoking.

If you'd like to try Varenicline tablets or Zyban (Bupropion) tablets in the UK, Ashcroft Online Pharmacy has both available in stock.

Cytisine vs varenicline

Cytisine and Varenicline are effective quit-smoking tablets; they differ in accessibility, efficacy, and structure. 

Cytisine is a plant-based alkaloid that binds to nicotinic acetylcholine receptors, reducing cravings and withdrawal symptoms (irritability, mood changes, etc.). On the other hand, Varenicline is a synthetic drug and works in the same way as Cytisine.

Varenicline is more effective than Cytisine, but the risk of side effects is higher in Varenicline than in Cytisine. 

Varenicline is slightly expensive, while Cytisine is an affordable solution. 

The selection between Cytisine and Varenicline depends on your medical history, budget, and personal preferences. So, consult your doctor for better advice. 

Cytisine vs nicotine replacement therapy (NRT)

Cytisine and NRT are reliable quit-smoking options, but they differ in mode of action and composition. 

  • Cytisine is a plant-based alkaloid that binds to nicotinic acetylcholine receptors, reducing cravings and withdrawal symptoms.

  • In contrast, NRT offers controlled doses of nicotine via patches, lozenges, sprays, or gums, letting you wean off addiction gradually.

  • NRT is slightly expensive, while Cytisine is an affordable solution.

  • Cytisine has higher effectiveness and quit rates than NRT. 

The selection between Cytisine and NRT depends on your budget, accessibility, and personal preferences. So, consult your doctor to determine the right fit for you.

Is It Right for You?

While stopping smoking without medicine is possible, the difficulty of the process varies for each person. Some may find it easier to quit with medication or other treatments like nicotine replacement therapy (NRT) or prescription drugs (like Varenicline or Zyban) to help manage cravings and withdrawal symptoms.

For some people, quitting smoking may lead to changes in thinking, behavior, and feelings of depression or anxiety, with rare cases of suicidal thoughts or worsening of psychiatric disorders.

If you’ve tried to quit before without medication and found it difficult, combining behavioral strategies with a medication or support program may increase your chances of success. Always discuss to a healthcare professional for guidance on the best approach for your needs.

Author
NameMr Suhail Jamil
RoleSuperintendent Pharmacist
GPHc Number2069518

 

Directions

Dosage

Cytisine dosage schedule

The Cytisine dosage schedule is as follows:

  • âś… Day 1-3: 1 tablet every 2 hours (6 tablets per day)

  • âś… Day 4-12: 1 tablet every 2.5 hours (5 tablets per day)

  • âś… Day 13-16: 1 tablet every 3 hours (4 tablets per day)

  • âś… Day 17-20: 1 tablet every 5 hours (3 tablets per day)

  • âś… Day 21-25: 1-2 tablets daily (2 tablets per day)

âś… Stick to your doctor’s guidelines and do not change the dose on your own as it may result in negative side effects. 

Warnings

Warnings and precautions of Cytisine

Cytisine is suitable for smokers between 18-65 of their age. However, you should not take Cytisine if you have:

  • Kidney, liver, or heart problems
  • A history of stroke
  • History of psychiatric disorders 
  • High blood pressure (hypertension)
  • Are pregnant or breastfeeding 
  • Are over 65 years
  • Are under 18 years
  • Pheochromocytoma (tumor in the adrenal glands)
  • Atherosclerosis (thickening or hardening of the arteries)
  • Other peripheral vascular diseases
  • Gastric and duodenal ulcer
  • Gastroesophageal reflux disease
  • Hyperthyroidism (overactive thyroid)
  • Diabetes
  • Schizophrenia
  • Allergy to Cytisine or any other ingredient present in this medication
  • Unstable angina 
  • Recent heart attack (myocardial infarction)
  • Clinically significant arrhythmias (abnormal/irregular heart rhythm)

Moreover, while taking Cytisine, women who are using hormonal contraception should also use additional barriers, such as condoms, to prevent pregnancy. This is because Cytisine makes the contraceptive pills less effective.

Interaction of Cytisine with other medications

The Cytisine 1.5mg tablet may interact with many prescription medications, OTC drugs, supplements, vitamins, and minerals, resulting in serious side effects. So before taking Cytisine, consult your doctor if you are taking any of these drugs such as:

  • Anti-tuberculosis drugs
  • Other stop-smoking medications
  • Medicines which contain theophylline (to treat asthma)
  • Drugs with Tacrine for Alzheimer’s disease
  • Medicine with Clozapine for schizophrenia
  • Drugs with Ropinirole to treat Parkinson’s disease
  • Cytisine and pregnancy & breastfeeding

You should not take Cytisine if you are pregnant or breastfeeding, as it may harm your baby. So, consult your doctor to determine the safe and effective treatment option for you. 

Cytisine and driving

Cytisine may cause dizziness, fatigue, or difficulty in concentration. If you notice these effects, avoid driving or operating heavy machinery to prevent accidents.

Cytisine tablet and weight loss 

Cytisine, a smoking cessation aid, has sparked interest for its role in weight loss. When it binds to nicotinic receptors, it not only reduces nicotine cravings but also regulates appetite and metabolic processes.

In some people, Cytisine suppresses appetite and gives them feelings of satiety, reducing calorie intake and promoting weight loss. 

FAQ

  • Is Cytisine available in the US?

    Cytisine is not approved by the FDA for use in the United States (US). However, it is widely available in Canada and European countries.

  • Is Cytisine FDA-approved?

    Cytisine is not FDA-approved. It was approved by the MHRA (medicines and Healthcare Products Regulatory Agency) to be used as an OTC natural product in Canada in 2017 and as a prescription medicine in the UK in January 2024. 

  • What does Cytisine do to the body?/How does Cytisine work?

    Cytisine acts as a partial agonist of nicotinic acetylcholine receptors and mimics the effects of nicotine with lower potency. It reduces withdrawal symptoms and nicotine cravings, making it effective for quitting smoking.

    However, it may cause some side effects, such as vomiting, sleep problems, or nausea in some people. 

  • How do I get Cytisine?

    You can get Cytisine online via Ashcroft Pharmacy. Just fill out an online consultation form and our pharmacists will figure out whether Cytisine is safe for you.

    Once approved, we will dispatch your medicine to your doorstep via our fast, discreet delivery process.

  • What is another name for Cytisine?

    Cytisine, also known as sophorine or baptitoxine, is derived from plant species such as Sophora and Cytisus spp. Due to its nicotine-like effects, cytosine is widely used in smoking cessation treatments. 

  • What are Cytisine's benefits?

    Cytisine tablet is an effective smoking cessation treatment. It stimulates nicotine receptors in your brain, alleviating nicotine cravings and withdrawal symptoms. It is an affordable treatment and also has a favorable safety profile compared to others, such as varenicline.

     

Side Effects

Cytisine Side Effects: What are the risks of Cytisine?

Cytisine causes some side effects in some people. It includes:

Common side effects

1 in 10 people get these effects. These symptoms resolve on their own within a few days; however, if they persist or get worse, consult your doctor. 

The common side effects of Cytisine pills are:

  • Changes in appetite (usually an increase)
  • Weight gain
  • Mood changes
  • Anxiety 
  • Dizziness
  • Sleep problems
  • High blood pressure (hypertension)
  • Headaches
  • Slow/increase heart rate
  • Diarrhea
  • Dry mouth
  • Sickness
  • Heartburn
  • Nausea
  • Fatigue
  • Muscle pain 
  • Rash
  • Vomiting
  • Abdominal pain
  • Changes flavor
  • Constipation

Serious side effects

1 in 100 people get these effects. If you experience any of these effects, seek emergency help or visit your doctor immediately. 

The serious side effects of Cytisine are:

  • Abdominal distension
  • Difficulty in concentration
  • Malaise 
  • Burning tongue
  • Decreased libido
  • The feeling of heaviness in the head
  • Lacrimation (abnormal or excessive secretion of tears)
  • Increased sputum (phlegm)
  • Dyspnea (shortness of breath)
  • Sweating
  • Excessive salivation
  • Tiredness
  • Decreased elasticity of the skin
  • Increase in serum transaminase levels

Ingredients

Cytisine ingredients 

Each tablet of Cytisine contains two types of ingredients:

Active ingredient: 1.5 mg of Cytisine
Inactive ingredients: Microcrystalline cellulose, mannitol, glycerol dibehenate, magnesium stearate, and hypromellose.

Delivery

Once your order has been approved by our UK medical team it will be dispatched via Royal mail. All orders are sent using a tracked and signed for service.


Royal Mail 48 (2-5 days) | £3.49

Estimated delivery within 2-3 working days. Excludes bank holidays. Not a guaranteed service.

Free delivery on orders over £50.

Royal Mail 24 (Next working day) | £4.99

Estimated delivery within 1 working day. Excludes bank holidays. Not a guaranteed service.

Royal Mail Special Delivery Guaranteed by 1pm | £6.99

Order by the 2:00 PM weekday cut-off time for guaranteed delivery by 1:00 PM the next business day.

Orders placed after the cut-off on Friday will be delivered on Tuesday.

Reviews

Cytisine reviews 

Cytisine has gained positive reviews all over the world, helping people quit smoking permanently. Some users reported that they had used many other options, such as gums, patches, and cold turkey; Cytisine is the only thing that worked.

The other users claimed that quitting smoking with Cytisine is easy as it offers mild side effects and fewer nicotine withdrawal effects, making quitting smoking journey tension-free. 

However, before using Cytisine, you must consult your doctor to determine whether Cytisine is a safe option for you. 

 

 

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Medication Ashcroft Pharmacy
1.5mg x100 Tablets £149.99
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